Clinical Niacinamide 20% Treatment

• WaterSolvent
• NiacinamideSkin Conditioning, Hair Conditioning, Smoothing

  Ingredient Notes

  Niacinamide is a B vitamin, but not one of the B vitamins linked to Malassezia. Growth work names thiamine (B1) and pyridoxine (B6) as increasing growth alongside a lipid, without being required for it. Thiamine is not food for the yeast: it speeds the step that turns an amino acid into the carbon skeleton it uses, and supplying that skeleton directly removes the need for thiamine entirely. B3 is not named in any of that work. We rate niacinamide safe on that evidence rather than treating the whole B group as one risk, and nothing we hold shows it treats fungal acne either.

  EWG1

  CIRS

  References

  • https://doi.org/10.1007/978-3-642-03616-3_4
  • https://doi.org/10.3181/00379727-58-14895
  • https://doi.org/10.1007/s004030050304
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605215/
  • https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.12481
  • https://pubmed.ncbi.nlm.nih.gov/25399625/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724370/
• Pentylene GlycolSolvent, Skin Conditioning
• Butylene GlycolSolvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
• GlycerinSolvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

  Ingredient Notes

  In a lab study, Malassezia was unable to grow on glycerin without the presence of fatty acids in the agar, indicating that it is not a fungal acne trigger.

  EWG2

  CIRS

  References

  • https://pubchem.ncbi.nlm.nih.gov/compound/Glycerol
  • https://www.ncbi.nlm.nih.gov/pubmed/18510666
  • https://www.ncbi.nlm.nih.gov/pubmed/11301638
  • https://www.mdpi.com/2079-9284/6/3/45
  • https://www.ncbi.nlm.nih.gov/pubmed/29737895
  • https://www.ncbi.nlm.nih.gov/pubmed/4128616
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC118058/
  • https://www.sciencedirect.com/science/article/pii/S0022202X15498574
  • http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHYY201307007.htm
  • https://pubmed.ncbi.nlm.nih.gov/25134312/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137500/
• Acetyl GlucosamineSkin Conditioning
• Ascorbyl GlucosideAntioxidant
• Glycyrrhiza Glabra (Licorice) Root ExtractSkin Conditioning, Perfuming, Humectant, Antioxidant
• Spiraea Ulmaria (Meadowsweet) ExtractSkin Conditioning, Tonic, Astringent
• Portulaca Oleracea ExtractAntioxidant, Anti-Microbial, Anti-Inflammatory, Skin Conditioning
• Camellia Japonica (Japanese Camellia) Flower ExtractSkin Conditioning, Emollient
• Epigallocatechin GallateAntioxidant
• Boerhavia Diffusa Root ExtractSkin Protecting
• Camellia Sinensis (Green Tea) Leaf ExtractSkin Conditioning, Masking, Emollient, Fragrance, Humectant, Antimicrobial, Skin Protecting, Uv Absorber, Antioxidant, Tonic, Astringent, Skin-Conditioning Agent -Miscellaneous
• AllantoinSkin Conditioning, Skin Protecting, Soothing, Anti-inflammatory, Keratolytic Agent
• LecithinSkin Conditioning, Emollient, Surfactant, Emulsifying, Antistatic Agent
• PullulanBinding Agent, Binding, Film Forming
• PanthenolSkin Conditioning, Anti-static Agent, Hair Conditioning
• SilicaViscosity Controlling, Abrasive, Absorbent, Bulking Agent, Opacifying, Anticaking Agent
• Xanthan GumSkin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant -Emulsifying Agent, Gel Forming
• Sclerotium GumSkin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilizing
• PropanediolSolvent, Viscosity Controlling, Viscosity Decreasing Agent
• Sodium PhytateChelating Agent
• PhenoxyethanolFragrance, Preservative
• EthylhexylglycerinSkin Conditioning, Deodorant

Packaging and formulations can change. Always verify the live box, bottle, or retailer ingredient list before use.